We're looking at an unusual condition, Feline Hyperesthesia (FHS). Although rare, it could explain why a cat appears twitchy and extremely oversensitive to touch.
If you think of a Truffle, you might think of a rare, prized delicacy, something to be treasured. Likewise, Truffle, the pretty tortoiseshell cat,
Anywhere that you live, you will be affected by the weather. And for each person it's different. Some love the humidity of the South