Male Sphynx Cat Found To Be Experiencing Gender Transition By Accident!

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A veterinarian in Prague saw something out of the ordinary from one of her patients recently. The owner had brought her beloved male Sphynx cat in for an exam due to enlarged mammary glands. Terrified as to why this was happening to her one-year-old male cat, she reported they had swollen in just 2 days time. 

For the staff at Prague Veterinary Clinic in the Czech Republic, the diagnosis was not easily determined.

At first, they checked to see if the swelling was due to tumors. Nope, samples of the lumps themselves showed no cancerous cells.

Next, they performed a sonogram on the poor sphynx boy. It was possible that a tumor had formed on his adrenal gland which would effect his hormones. 

“As part of your endocrine system, the adrenal glands produce hormones. They give instructions to virtually every organ and tissue in your body”, explains

The results of those tests were negative as well. They eliminated the possibility that he had any tumors in his testicles. They checked anything else that could be tied to the mammary glands. Covering all bases, they confirmed the cat was also not a hermaphrodite. This occurs when one has both male and female reproductive organs.

Nothing produced answers and they were forced to wait for the blood test results to come back. 

When veterinarian MVDr. Martina Načeradská received the results, she was shocked at what they were showing.

“The lab confirmed an extreme increase in estrogen levels, so high that they were afraid to communicate it,” she admitted to “They were convinced that it was a measurement error.”

MVDr. Martina Načeradská

Reportedly, the male’s estrogen levels were higher than that of a female cat…in heat! 

They discussed with the frightened woman just what may have caused this reaction. One theory they focused on was medications around the home the cat could have gotten into.

Although she knew the cat hadn’t eaten any pills, what they eventually discovered was just as dangerous. 

Over the 4 months prior to the issue, the woman had undergone a gender transformation. (Seems pretty obvious they should have linked the two quicker in my opinion.) The process includes numerous hormone related prescriptions. One of those was Lenzetto, used in Hormone Replacement Therapy (HRT). 

According to the Lenzetto leaflet insert, “It contains a female hormone, from the group of oestrogens. Lenzetto is used in postmenopausal women with at least 6 months since their last natural period. [It] can also be used in women who have had surgery to remove their ovaries as this causes instant menopause.”

Lenzetto is a spray solution which contains small amounts of a medicine called estradiol. When sprayed onto the skin as directed, it passes through the skin into your bloodstream.

Sadly, after using the spray, the woman didn’t wash her hands before snuggling with her beloved cat.

It’s even worse when the application site is on the inner forearm…a favorite kitty spot. Now imagine what it does to a 10 pound cat with no fur to lessen the exposure. The vet believes the coincidence that it was a sphynx cat made for a worst case scenario. It was as if the cat was joining his owner during the gender transformation.

Happily, as rare as it was to discover, the solution was simple. Wash up after using and keep the cat away from the application site.

Eventually the swelling decreased and the fortunate feline is back to normal–with one relieved mom!


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